

| Numéro de catalogue | HA938014 | ||||||||
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| Description |
Anti-MFN1 Polyclonal Antibody (HA938014) is a rabbit polyclonal antibody detecting MFN1 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant MFN1 (Met1-Gly298). | ||||||||
| Cible | EC:3.6.5.-, Fzo homolog, MFN1, Mitofusin-1, Transmembrane GTPase MFN1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8IWA4, Q8R4Z9, Q811U4 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Mitofusin-1 (MFN1) is a ~84 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro). 1. Legros, F. et al. (2002) Molecular biology of the cell 13, 4343-54. PMID: 12475957 2. Santel, A. et al. (2003) Journal of cell science 116, 2763-74. PMID: 12759376 3. Qi, Y. et al. (2016) The Journal of cell biology 215, 621-629. PMID: 27920125 4. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303 | ||||||||
| Note | For research use only |
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