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| カタログ番号 | HA938014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MFN1 Polyclonal Antibody (HA938014) is a rabbit polyclonal antibody detecting MFN1 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant MFN1 (Met1-Gly298). | ||||||||
| ターゲット | EC:3.6.5.-, Fzo homolog, MFN1, Mitofusin-1, Transmembrane GTPase MFN1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8IWA4, Q8R4Z9, Q811U4 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Mitofusin-1 (MFN1) is a ~84 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro). 1. Legros, F. et al. (2002) Molecular biology of the cell 13, 4343-54. PMID: 12475957 2. Santel, A. et al. (2003) Journal of cell science 116, 2763-74. PMID: 12759376 3. Qi, Y. et al. (2016) The Journal of cell biology 215, 621-629. PMID: 27920125 4. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303 | ||||||||
| 注意事項 | For research use only |
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