Anti-MFN2 Polyclonal Antibody (HF769014)

Name: Anti-MFN2 Polyclonal Antibody
Brand: abinScience
SKU: HF769014
Price: 168 USD
Availability: InStock

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Referencias
Datasheet
SDS

Vista general

Número de catálogo

HF769014

Descripción

Anti-MFN2 Polyclonal Antibody (HF769014) is a rabbit polyclonal antibody detecting MFN2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human MFN2 (His20-Arg400).

Objetivo

Transmembrane GTPase MFN2, Mitofusin-2, KIAA0214, CPRP1, MFN2

Purificación

Purified by antigen affinity column.

Número de acceso

O95140

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Mitofusin-2 (MFN2) is a ~86 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes.

1. Santel, A. et al. (2001) Journal of cell science 114, 867-74. PMID: 11181170

2. Rojo, M. et al. (2002) Journal of cell science 115, 1663-74. PMID: 11950885

3. Casasnovas, C. et al. (2010) Journal of medical genetics 47, 249-56. PMID: 19889647

4. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

5. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303

6. Chen, Y. et al. (2013) Science (New York, N.Y.) 340, 471-5. PMID: 23620051

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-MFN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo