Anti-MFN2 Polyclonal Antibody (HF769014)

Name: Anti-MFN2 Polyclonal Antibody
Brand: abinScience
SKU: HF769014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HF769014

Description

Anti-MFN2 Polyclonal Antibody (HF769014) is a rabbit polyclonal antibody detecting MFN2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human MFN2 (His20-Arg400).

Cible

Transmembrane GTPase MFN2, Mitofusin-2, KIAA0214, CPRP1, MFN2

Purification

Purified by antigen affinity column.

Numéro d'accès

O95140

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Mitofusin-2 (MFN2) is a ~86 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes.

1. Santel, A. et al. (2001) Journal of cell science 114, 867-74. PMID: 11181170

2. Rojo, M. et al. (2002) Journal of cell science 115, 1663-74. PMID: 11950885

3. Casasnovas, C. et al. (2010) Journal of medical genetics 47, 249-56. PMID: 19889647

4. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

5. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303

6. Chen, Y. et al. (2013) Science (New York, N.Y.) 340, 471-5. PMID: 23620051

Note

For research use only.

Images

Reférences

Fiche technique

Anti-MFN2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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