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Anti-MGLL Polyclonal Antibody (HV516014)

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Vista general
Número de catálogoHV516014
Descripción
Anti-MGLL Polyclonal Antibody (HV516014) is a rabbit polyclonal antibody detecting MGLL in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human MGLL (Met1-Pro303).
Objetivo Lysophospholipase-like, MGLL, Monoacylglycerol lipase, Lysophospholipase homolog, MGL, Monoglyceride lipase, HU-K5, MAGL
Purificación Purified by antigen affinity column.
Número de acceso Q99685
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Monoglyceride lipase (MGLL) is a ~33 kDa protein. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.

1. Long, JZ. et al. (2009) Nature chemical biology 5, 37-44. PMID: 19029917
2. Nomura, DK. et al. (2010) Cell 140, 49-61. PMID: 20079333
3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984
4. Navia-Paldanius, D. et al. (2012) Journal of lipid research 53, 2413-24. PMID: 22969151
5. Laitinen, T. et al. (2014) Molecular pharmacology 85, 510-9. PMID: 24368842
Nota For research use only.
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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