

| Numéro de catalogue | HV516014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MGLL Polyclonal Antibody (HV516014) is a rabbit polyclonal antibody detecting MGLL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MGLL (Met1-Pro303). | ||||||||
| Cible | Lysophospholipase-like, MGLL, Monoacylglycerol lipase, Lysophospholipase homolog, MGL, Monoglyceride lipase, HU-K5, MAGL | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q99685 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Monoglyceride lipase (MGLL) is a ~33 kDa protein. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. 1. Long, JZ. et al. (2009) Nature chemical biology 5, 37-44. PMID: 19029917 2. Nomura, DK. et al. (2010) Cell 140, 49-61. PMID: 20079333 3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 4. Navia-Paldanius, D. et al. (2012) Journal of lipid research 53, 2413-24. PMID: 22969151 5. Laitinen, T. et al. (2014) Molecular pharmacology 85, 510-9. PMID: 24368842 | ||||||||
| Note | For research use only. |
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