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| カタログ番号 | HV516014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MGLL Polyclonal Antibody (HV516014) is a rabbit polyclonal antibody detecting MGLL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MGLL (Met1-Pro303). | ||||||||
| ターゲット | Lysophospholipase-like, MGLL, Monoacylglycerol lipase, Lysophospholipase homolog, MGL, Monoglyceride lipase, HU-K5, MAGL | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q99685 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Monoglyceride lipase (MGLL) is a ~33 kDa protein. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. 1. Long, JZ. et al. (2009) Nature chemical biology 5, 37-44. PMID: 19029917 2. Nomura, DK. et al. (2010) Cell 140, 49-61. PMID: 20079333 3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 4. Navia-Paldanius, D. et al. (2012) Journal of lipid research 53, 2413-24. PMID: 22969151 5. Laitinen, T. et al. (2014) Molecular pharmacology 85, 510-9. PMID: 24368842 | ||||||||
| 注意事項 | For research use only. |
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