

| Numéro de catalogue | HY437014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MMP1 Polyclonal Antibody (HY437014) is a rabbit polyclonal antibody detecting MMP1 in ELISA, IHC, WB. Suitable for Human, Bovine, Equus caballus, and Pig.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human MMP1 (Phe20-Asn469). | ||||||||
| Cible | MMP1, MMP-1, Matrix metalloproteinase-1, CLG, Interstitial collagenase, Fibroblast collagenase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P03956 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Interstitial collagenase (MMP1) is a ~54 kDa protein. Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity. 1. Desrochers, PE. et al. (1991) The Journal of clinical investigation 87, 2258-65. PMID: 1645757 2. Springman, EB. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 364-8. PMID: 2153297 3. Clark, IM. et al. (1989) The Biochemical journal 263, 201-6. PMID: 2557822 4. Rumbaugh, J. et al. (2006) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20, 1736-8. PMID: 16807369 | ||||||||
| Note | For research use only. |
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