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| カタログ番号 | HW650014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-MMP13 Polyclonal Antibody (HW650014) is a rabbit polyclonal antibody detecting MMP13 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Equus caballus.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human MMP13 (Leu20-Cys471). | ||||||||
| ターゲット | MMP-13, MMP13, Matrix metalloproteinase-13, Collagenase 3 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P45452 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Collagenase 3 (MMP13) is a ~53 kDa protein. Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. | ||||||||
| 注意事項 | For research use only. |
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