

| Numéro de catalogue | HB353014 | ||||||||
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| Description |
Anti-MORN3 Polyclonal Antibody (HB353014) is a rabbit polyclonal antibody detecting MORN repeat-containing protein 3; MORN3 in ELISA, IHC, WB. Suitable for Human and Bovine.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human MORN3 (Met1-Asp240). | ||||||||
| Cible | MORN repeat-containing protein 3; MORN3 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6PF18, Q32KM6 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | MORN repeat-containing protein 3 (MORN3) is a ~27 kDa protein. Assembles a suppression complex (suppresome) by tethering SIRT1 and MDM2 to regulate composite modifications of p53/TP53. Confers both deacetylation-mediated functional inactivation, by SIRT1, and ubiquitination-dependent degradation, by MDM2, of p53/TP53, promoting a proliferative and cell survival behaviors. May play a role in the regulation of spermatogenesis. 1. Liang, L. et al. (2018) Cell chemical biology 25, 761-774.e5. PMID: 29681526 | ||||||||
| Note | For research use only |
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