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| カタログ番号 | MF562014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse ADA/Adenosine deaminase Polyclonal Antibody (MF562014) is a rabbit polyclonal antibody detecting Adenosine deaminase in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse ADA/Adenosine deaminase (Met1-Gln352). | ||||||||
| ターゲット | Adenosine deaminase, 3.5.4.4, Adenosine aminohydrolase, Ada | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P03958 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Adenosine deaminase (ADA) is a ~39 kDa protein. Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. 1. Xu, PA. et al. (2000) Biochemical and biophysical research communications 269, 749-57. PMID: 10720488 2. Mohamedali, KA. et al. (1996) Biochemistry 35, 1672-80. PMID: 8634299 3. Sideraki, V. et al. (1996) Biochemistry 35, 7862-72. PMID: 8672487 4. Sideraki, V. et al. (1996) Biochemistry 35, 15019-28. PMID: 8942668 5. Blackburn, MR. et al. (1997) Development (Cambridge, England) 124, 3089-97. PMID: 9272950 6. Apasov, SG. et al. (2001) The Journal of clinical investigation 108, 131-41. PMID: 11435465 7. Li, G. et al. (2015) Pharmacology research & perspectives 3, e00121. PMID: 26038697 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-ADA polyclonal antibody at ADA on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MOLT-4 cell lysate
Lane 3: Mouse thymus lysate
Lane 4: Mouse stomach lysate
Lane 5: Rat spleen lysate
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