Anti-Mouse ANGPTL4 Recombinant Antibody (6G11) (HV344033)

Name: Anti-Mouse ANGPTL4 Recombinant Antibody (6G11)
Brand: abinScience
SKU: HV344033
Price: 196 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HV344033

Reactividad de especies

Mouse

Aplicaciones

ELISA, Neutralization

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

6G11

Objetivo

Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, ANGPTL4 N-terminal chain, ANGPTL4 C-terminal chain, Angptl4, Farp, Fiaf, Ng27

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9Z1P8

RRID

Anti-Mouse ANGPTL4 Antibody (6G11) (abinScience Cat# HV344033, RRID:AB_3729336)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Angiopoietin-related protein 4 (ANGPTL4) is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis (Probable).

1. Xu, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 6086-91. PMID: 15837923

2. Desai, U. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11766-71. PMID: 17609370

3. Gusarova, V. et al. (2018) Nature communications 9, 2252. PMID: 29899519

4. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458

5. Galaup, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 18721-6. PMID: 17130448

6. Perdiguero, EG. et al. (2011) The Journal of biological chemistry 286, 36841-51. PMID: 21832056

Nota

For research use only.

Imágenes