Anti-Mouse ANGPTL4 Recombinant Antibody (6G11) (HV344033)

Name: Anti-Mouse ANGPTL4 Recombinant Antibody (6G11)
Brand: abinScience
SKU: HV344033
Price: 196 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HV344033

Reactivité des espèces

Mouse

Applications

ELISA, Neutralization

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

6G11

Cible

Angiopoietin-related protein 4, 425O18-1, Angiopoietin-like protein 4, Fasting-induced adipose factor, Hepatic fibrinogen/angiopoietin-related protein, HFARP, Secreted protein Bk89, ANGPTL4 N-terminal chain, ANGPTL4 C-terminal chain, Angptl4, Farp, Fiaf, Ng27

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9Z1P8

RRID

Anti-Mouse ANGPTL4 Antibody (6G11) (abinScience Cat# HV344033, RRID:AB_3729336)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Angiopoietin-related protein 4 (ANGPTL4) is a ~45 kDa protein. Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stress fibers and focal adhesions in endothelial cells that have adhered to ANGPTL4-containing ECM (in vitro). Depending on context, may modulate tumor-related angiogenesis (Probable).

1. Xu, A. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 6086-91. PMID: 15837923

2. Desai, U. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11766-71. PMID: 17609370

3. Gusarova, V. et al. (2018) Nature communications 9, 2252. PMID: 29899519

4. Ito, Y. et al. (2003) Cancer research 63, 6651-7. PMID: 14583458

5. Galaup, A. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 18721-6. PMID: 17130448

6. Perdiguero, EG. et al. (2011) The Journal of biological chemistry 286, 36841-51. PMID: 21832056

Note

For research use only.

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