Anti-Mouse ApoE Recombinant Antibody (HJ6.3) (MF739013)

Name: Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
Brand: abinScience
SKU: MF739013
Price: 110 USD
Availability: InStock

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1mg

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Datasheet
SDS

Vista general

Número de catálogo	MF739013
Reactividad de especies	Mouse
Aplicaciones	Blocking, IHC
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	HJ6.3
Objetivo	Apo-E, Apolipoprotein E, APOE
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P08226
RRID	Anti-Mouse APOE Antibody (HJ6.3) (abinScience Cat# MF739013, RRID:AB_3725650)
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Apolipoprotein E (APOE) is a ~35 kDa protein. APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. 1. Gonzales, JC. et al. (2013) The Journal of clinical investigation 123, 2742-51. PMID: 23676495
Nota	For research use only.

Imágenes

Bioactivity

SEC-HPLC detection for Anti-Mouse APOE Antibody (HJ6.3).
SDS-PAGE

SDS-PAGE for Anti-Mouse APOE Antibody (HJ6.3).
Western blot

Western blot analysis was performed using anti-APOE monoclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse liver lysate
Lane 2: Mouse brain lysate
Lane 3: Mouse heart lysate