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Anti-Mouse ApoE Recombinant Antibody (HJ6.3) (MF739013)

Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
Anti-Mouse ApoE Recombinant Antibody (HJ6.3)
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Aperçu
Numéro de catalogueMF739013
Reactivité des espècesMouse
ApplicationsBlocking, IHC
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneHJ6.3
Cible Apo-E, Apolipoprotein E, APOE
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P08226
RRID Anti-Mouse APOE Antibody (HJ6.3) (abinScience Cat# MF739013, RRID:AB_3725650)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Apolipoprotein E (APOE) is a ~35 kDa protein. APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.

1. Gonzales, JC. et al. (2013) The Journal of clinical investigation 123, 2742-51. PMID: 23676495
Note For research use only.
Images
  • Anti-Mouse ApoE Recombinant Antibody (HJ6.3)

    Bioactivity

    SEC-HPLC detection for Anti-Mouse APOE Antibody (HJ6.3).

  • Anti-Mouse ApoE Recombinant Antibody (HJ6.3)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse APOE Antibody (HJ6.3).

  • Anti-Mouse ApoE Recombinant Antibody (HJ6.3)

    Western blot

    Western blot analysis was performed using anti-APOE monoclonal antibody at 1ug/mL on various samples.
    Lane 1: Mouse liver lysate
    Lane 2: Mouse brain lysate
    Lane 3: Mouse heart lysate

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
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C₂ (Working Conc.)
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Recommandation

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