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| カタログ番号 | MS942014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse Arl13b Polyclonal Antibody (MS942014) is a rabbit polyclonal antibody detecting ARL13B. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse Arl13b (Met1-Ser241). | ||||||||
| ターゲット | ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL13B, ARL2-like protein 1, ARL2L1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q640N2 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | ADP-ribosylation factor-like protein 13B (Arl13b) is a ~48 kDa protein. Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. 1. Higginbotham, H. et al. (2013) Nature neuroscience 16, 1000-7. PMID: 23817546 2. Higginbotham, H. et al. (2012) Developmental cell 23, 925-38. PMID: 23153492 | ||||||||
| 注意事項 | For research use only. |
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