Anti-Mouse CCL20/MIP-3-alpha Recombinant Antibody (SAA2679) (MX131013)

Name: Anti-Mouse CCL20/MIP-3-alpha Recombinant Antibody (SAA2679)
Brand: abinScience
SKU: MX131013
Price: 191 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo	MX131013
Reactividad de especies	Mouse
Aplicaciones	ELISA, Neutralization
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	SAA2679
Objetivo	Beta-chemokine exodus-1, C-C motif chemokine 20, CC chemokine LARC, CC chemokine ST38, Ccl20, Larc, Liver and activation-regulated chemokine, MIP-3-alpha, Macrophage inflammatory protein 3 alpha, Scya20, Small-inducible cytokine A20
Nivel de endotoxinas	<10 EU/mg
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O89093
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	C-C motif chemokine 20 (CCL20/MIP-3-alpha) is a ~10 kDa protein. Acts as a ligand for C-C chemokine receptor CCR6. Signals through binding and activation of CCR6 and induces a strong chemotactic response and mobilization of intracellular calcium ions. The ligand-receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic cells (DC), effector/memory T-cells and B-cells and plays an important role at skin and mucosal surfaces under homeostatic and inflammatory conditions, as well as in pathology, including cancer and autoimmune diseases. CCL20 acts as a chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Involved in the recruitment of both the pro-inflammatory IL17 producing helper T-cells (Th17) and the regulatory T-cells (Treg) to sites of inflammation. 1. Röhrl, J. et al. (2010) The Journal of biological chemistry 285, 7028-34. PMID: 20068036 2. Varona, R. et al. (1998) FEBS letters 440, 188-94. PMID: 9862452 3. Ito, T. et al. (2011) Experimental cell research 317, 613-9. PMID: 21376174 4. Yamazaki, T. et al. (2008) Journal of immunology (Baltimore, Md. : 1950) 181, 8391-401. PMID: 19050256 5. Bunting, MD. et al. (2014) Immunology and cell biology 92, 489-98. PMID: 24638065 6. Diao, R. et al. (2014) Science translational medicine 6, 249ra108. PMID: 25122636 7. Tanaka, Y. et al. (1999) European journal of immunology 29, 633-42. PMID: 10064080
Nota	For research use only

Imágenes

Referencias

Datasheet

Anti-Mouse CCL20/MIP-3-alpha Recombinant Antibody (SAA2679).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo