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Anti-Mouse CD193/CCR3 Recombinant Antibody (6S2-19-4) (MW620013)

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  • 50ug
  • 100ug
  • 1mg
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Aperçu
Numéro de catalogueMW620013
Reactivité des espècesMouse
ApplicationsELISA, FCM, Functional assay, Research in vivo
Espèce hôteRat
ClonalitéMonoclonal
IsotypeIgG2b, kappa
ID de clone6S2-19-4
Cible C C CKR3, C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CCR3, CD193, CKR 3, CKR3, CMKBR3, Eosinophil eotaxin receptor
Niveau d'endotoxines < 10 EU/mg
Pureté >95% as determined by SDS-PAGE.
Produits associés pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P51678
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Expédition In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Probable C-C chemokine receptor type 3 (CCR3/CD193) is a ~41 kDa protein. G protein-coupled receptor (GPCR) that plays a key role in the immune system by regulating the migration and activation of white blood cells in response to chemokines. Selectively interacts with eosinophil-attracting chemokines such as eotaxin/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. Ligand binding triggers intracellular signaling that leads to chemotaxis of immune cells. Mechanistically, signals through GNA14 or GNA16 to induce stimulation of phospholipase Cbeta/PLCB2 and subsequently chemotaxis. Alternatively, transduces signal via GNAI1 resulting in elevated intracellular calcium levels and activation of the PI3K/AKT pathway.

Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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