

| Numéro de catalogue | MB604014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Mouse Endoglin/CD105 Polyclonal Antibody (MB604014) is a rabbit polyclonal antibody detecting Endoglin/CD105 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse CD105/ENG (Asp37-Gly332). | ||||||||
| Cible | Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105) | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q63961 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Arthur, HM. et al. (2000) Developmental biology 217, 42-53. PMID: 10625534 2. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 3. Sugden, WW. et al. (2017) Nature cell biology 19, 653-665. PMID: 28530658 4. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 | ||||||||
| Note | For research use only. |



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