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| カタログ番号 | MB604014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse Endoglin/CD105 Polyclonal Antibody (MB604014) is a rabbit polyclonal antibody detecting Endoglin/CD105 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD105/ENG (Asp37-Gly332). | ||||||||
| ターゲット | Endoglin (Cell surface MJ7/18 antigen) (CD antigen CD105) | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q63961 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis. 1. Arthur, HM. et al. (2000) Developmental biology 217, 42-53. PMID: 10625534 2. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773 3. Sugden, WW. et al. (2017) Nature cell biology 19, 653-665. PMID: 28530658 4. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529 | ||||||||
| 注意事項 | For research use only. |
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