Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4), APC (MB805237)

Name: Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4), APC
Brand: abinScience
SKU: MB805237
Price: 214 USD
Availability: InStock

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Número de catálogo	MB805237
Reactividad de especies	Mouse
Aplicaciones	FCM
Especie huésped	Rat
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	M17/4
Conjugación	APC
Objetivo	CD11A, Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, CD11 antigen-like family member A, CD11a, ITGAL, Integrin alpha-L
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Rat IgG2a, kappa Recombinant Isotype Control Antibody (RTK2758), APC
Número de acceso	P24063
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Integrin alpha-L (CD11a/ITGAL) is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. 1. Kaufmann, Y. et al. (1991) Journal of immunology (Baltimore, Md. : 1950) 147, 369-74. PMID: 2051027 2. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055 3. Liu, Z. et al. (2006) Blood 107, 1063-9. PMID: 16234355 4. Jiang, E. et al. (2014) Arteriosclerosis, thrombosis, and vascular biology 34, 34-43. PMID: 24158516 5. Bose, TO. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2863-72. PMID: 25108025
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4), APC.pdf

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