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Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4) (MB805207)

Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4)
Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4)
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  • 100ug
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  • Datasheet

  • SDS

Vista general
Número de catálogoMB805207
Reactividad de especiesMouse
AplicacionesFCM
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonM17/4
Objetivo CD11A, Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, CD11 antigen-like family member A, CD11a, ITGAL, Integrin alpha-L
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P24063
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Integrin alpha-L (CD11a/ITGAL) is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity.

1. Kaufmann, Y. et al. (1991) Journal of immunology (Baltimore, Md. : 1950) 147, 369-74. PMID: 2051027
2. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055
3. Liu, Z. et al. (2006) Blood 107, 1063-9. PMID: 16234355
4. Jiang, E. et al. (2014) Arteriosclerosis, thrombosis, and vascular biology 34, 34-43. PMID: 24158516
5. Bose, TO. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2863-72. PMID: 25108025
Nota For research use only.
Imágenes
  • Anti-Mouse Integrin alpha L/CD11a Recombinant Antibody (M17/4)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD11a/ITGAL Antibody (M17/4)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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