Anti-Mouse CTLA-4 Recombinant Antibody (9D9) (MB651207)

Name: Anti-Mouse CTLA-4 Recombinant Antibody (9D9)
Brand: abinScience
SKU: MB651207
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MB651207
Reactivité des espèces	Mouse
Applications	in vivo CTLA-4 neutralization, WB, in vivo intra-tumoral regulatory T cell depletion
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2b, kappa
ID de clone	9D9
Cible	CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P09793
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Note	For research use only.

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Bioactivity

Detects CD152/CTLA4 in indirect ELISAs.
Bioactivity

Detects recombinant mouse CD152/CTLA4 (Catalog No: MB651011) in indirect ELISA

Reférences

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

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Working Solution

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Aperçu