Anti-Mouse CTLA-4 Recombinant Antibody (H11) (MB651107)

Name: Anti-Mouse CTLA-4 Recombinant Antibody (H11)
Brand: abinScience
SKU: MB651107
Price: 191 USD
Availability: InStock

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Обзор

Каталожный номер	MB651107
Реактивность видов	Mouse
Применения	ELISA, FCM
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	VHH, mFc
ID клона	H11
Проверенные приложения	FCM
Цель	CD152, CTLA-4, CTLA4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Уровень эндотоксинов	< 10 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P09793
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Cytotoxic T-lymphocyte protein 4 (CD152/CTLA4) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. CD152 is the therapeutic target of ipilimumab (Yervoy).
Примечание	For research use only.

Изображения

Flow Cytometry

Flow-cytometry using anti-mouse CD152 antibody.CD152 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-mouse CD152 antibody monoclonal antibody (Catalog # MB651107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Bioactivity

Detects recombinant mouse CD152/CTLA4 (Catalog No: MB651011) in indirect ELISA

Ссылки

Даташит

Anti-Mouse CTLA-4 Recombinant Antibody (H11).pdf

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Formula

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