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Anti-Mouse CD160 Polyclonal Antibody
Anti-Mouse CD160 Polyclonal Antibody
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Обзор
Каталожный номерMF985014
Описание
Anti-Mouse CD160 Polyclonal Antibody (MF985014) is a rabbit polyclonal antibody detecting CD160 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Реактивность видовMouse
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Mouse CD160 (Ile30-Gln146).
Цель Natural killer cell receptor BY55, CD160 antigen, CD160, BY55
Очистка Purified by antigen affinity column.
Номер доступа O88875
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

CD160 antigen is a ~20 kDa protein. Receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta chain in activated T cells. Receptor for both classical and non-classical MHC class I molecules. Receptor or ligand for TNF superfamily member TNFRSF14, participating in bidirectional cell-cell contact signaling between antigen presenting cells and lymphocytes. Upon ligation of TNFRSF14, provides stimulatory signal to NK cells enhancing IFNG production and anti-tumor immune response.

1. Maeda, M. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 4426-32. PMID: 16177084
2. Tu, TC. et al. (2015) The Journal of experimental medicine 212, 415-29. PMID: 25711213
3. Shui, JW. et al. (2012) Nature 488, 222-5. PMID: 22801499
Примечание For research use only.
Изображения
  • Anti-Mouse CD160 Polyclonal Antibody

    Western blot

    Lane 1: Rat kidney lysate

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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