Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody (MV234014)

Name: Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody
Brand: abinScience
SKU: MV234014
Price: 168 USD
Availability: InStock

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MV234014

Descripción

Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody (MV234014) is a rabbit polyclonal antibody detecting SIGLEC1. Suitable for Mouse.

Reactividad de especies

Mouse

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Mouse CD169/SIGLEC1 (Gly22-Val235).

Objetivo

CD169, SIGLEC1, SN, Sialic acid-binding Ig-like lectin 1, Sialoadhesin, Siglec-1

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

Q62230

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Sialoadhesin (CD169/SIGLEC1) is a ~182 kDa protein. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response. Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs). In turn, enhances macrophage-to-T-cell transmission of several viruses including murine leukemia virus. Acts as an endocytic receptor mediating clathrin dependent endocytosis.

1. Chang, YC. et al. (2014) Journal of molecular medicine (Berlin, Germany) 92, 951-9. PMID: 24788876

2. Erikson, E. et al. (2015) The Journal of biological chemistry 290, 27345-27359. PMID: 26370074

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Mouse CD169/SIGLEC1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo