Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817) (MX892107)

Name: Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817)
Brand: abinScience
SKU: MX892107
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MX892107
Reactivité des espèces	Mouse
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	SAA0817
Cible	BIT, Bit, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, SIRP, SIRPA, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84
Niveau d'endotoxines	< 10 EU/mg
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P97797
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Tyrosine-protein phosphatase non-receptor type substrate 1 (CD172a/SIRPA) is a ~56 kDa protein. Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. 1. Nakaishi, A. et al. (2008) Journal of molecular biology 375, 650-60. PMID: 18045614 2. Sarute, N. et al. (2019) PLoS biology 17, e3000137. PMID: 30726215
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Mouse CD172a/SIRPA Antibody (SAA0817)

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Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817).pdf

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