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Anti-Mouse IL-18 R alpha Polyclonal Antibody (MC691014)

Anti-Mouse IL-18 R alpha Polyclonal Antibody
Anti-Mouse IL-18 R alpha Polyclonal Antibody
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概要
カタログ番号MC691014
説明
Anti-Mouse IL-18 R alpha Polyclonal Antibody (MC691014) is a rabbit polyclonal antibody detecting IL-18 R alpha in ELISA, IHC, WB. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Mouse
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Mouse CD218a/IL18R1 (Lys20-Lys314).
ターゲット Interleukin-18 receptor 1 (IL-18R-1) (IL-18R1) (EC 3.2.2.6) (CD218 antigen-like family member A) (IL1 receptor-related protein) (IL-1Rrp) (IL1R-rp) (Interleukin-18 receptor alpha) (IL-18R-alpha) (IL-18Ralpha) (CD antigen CD218a)
エンドトキシンレベル Please contact with the lab for this information.
純度 >95% as determined by SDS-PAGE.
精製 Purified by antigen affinity column.
アクセッション番号 Q61098
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-18 receptor 1 (CD218a/IL18R1) is a ~61 kDa protein. Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells. Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3.

1. Wang, J. et al. (2015) Nature medicine 21, 820-6. PMID: 26099046
注意事項 For research use only.
イメージ
  • Anti-Mouse IL-18 R alpha Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-IL18R1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: Jurkat cell lysate

参考文献
Formula
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