Anti-Mouse PrPC Recombinant Antibody (POM1) (MY392307)

Name: Anti-Mouse PrPC Recombinant Antibody (POM1)
Brand: abinScience
SKU: MY392307
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	MY392307
Marca	abinScience
Reactividad de especies	Human, Mouse, Bovine, Hamster
Aplicaciones	ELISA, FCM
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	POM1
Aplicaciones probadas	WB
Objetivo	Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P04925
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. 1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622 2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732 3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475 4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430
Nota	For research use only.

Imágenes

Bioactivity

Detects Human CD230/PRNP in indirect ELISAs.
Western blot

Western blot analysis was performed using anti-CD230/PRNP monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD230/PRNP (Catalog No: HY392011)
Lane 2: negative control