Anti-Mouse PrPC Recombinant Antibody (POM1) (MY392307)

Name: Anti-Mouse PrPC Recombinant Antibody (POM1)
Brand: abinScience
SKU: MY392307
Price: 191 USD
Availability: InStock

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Aperçu

Numéro de catalogue	MY392307
Marque	abinScience
Reactivité des espèces	Human, Mouse, Bovine, Hamster
Applications	ELISA, FCM
Espèce hôte	Mouse
Clonalité	Monoclonal
Isotype	IgG2a, kappa
ID de clone	POM1
Applications testées	WB
Cible	Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P04925
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. 1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622 2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732 3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475 4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430
Note	For research use only.

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Bioactivity

Detects Human CD230/PRNP in indirect ELISAs.
Western blot

Western blot analysis was performed using anti-CD230/PRNP monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD230/PRNP (Catalog No: HY392011)
Lane 2: negative control