

| Каталожный номер | MF564014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Mouse B7-H2 Polyclonal Antibody (MF564014) is a rabbit polyclonal antibody detecting B7-H2 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Реактивность видов | Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Mouse CD275/ICOSLG (Glu47-Gln258). | ||||||||
| Цель | ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD antigen CD275) | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9JHJ8 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | ICOS ligand (CD275/ICOSLG) is a ~35 kDa protein. Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (Probable). During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype. 1. Swallow, MM. et al. (1999) Immunity 11, 423-32. PMID: 10549624 2. Yoshinaga, SK. et al. (1999) Nature 402, 827-32. PMID: 10617205 3. Ling, V. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 1653-7. PMID: 10657606 | ||||||||
| Примечание | For research use only. |
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