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Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382) (MT188023)

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382)
Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382)
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  • 20ug
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  • 1mg
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Vista general
Número de catálogoMT188023
Reactividad de especiesMouse
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoVHH-mFc
ID de clonSAA2382
Objetivo Toll-like receptor 2, CD282, Tlr2
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso Q9QUN7
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.

1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042
2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091
3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712
4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456
5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037
Nota For research use only
Isotype Control Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)
Imágenes
  • Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD282/TLR2 Antibody (SAA2382)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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