Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382) (MT188023)

Name: Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382)
Brand: abinScience
SKU: MT188023
Price: 126 USD
Availability: InStock

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

MT188023

Reactivité des espèces

Mouse

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

VHH-mFc

ID de clone

SAA2382

Cible

Toll-like receptor 2, CD282, Tlr2

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q9QUN7

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.

1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042

2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091

3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712

4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456

5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037

Note

For research use only

Isotype Control

Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse CD282/TLR2 Antibody (SAA2382)

Reférences

Fiche technique

Anti-Mouse CD282/TLR2 Recombinant Antibody (SAA2382).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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