

| Каталожный номер | MT188023 | ||||
|---|---|---|---|---|---|
| Реактивность видов | Mouse | ||||
| Применения | ELISA | ||||
| Хозяинский вид | Mouse | ||||
| Клоональность | Monoclonal | ||||
| Изотип | VHH-mFc | ||||
| ID клона | SAA2382 | ||||
| Цель | Toll-like receptor 2, CD282, Tlr2 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Чистота | >95% as determined by SDS-PAGE. | ||||
| Очистка | Protein A/G purified from cell culture supernatant. | ||||
| Номер доступа | Q9QUN7 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Toll-like receptor 2 (CD282/TLR2) is a ~89 kDa protein. Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. 1. Hoebe, K. et al. (2005) Nature 433, 523-7. PMID: 15690042 2. Pathak, SK. et al. (2007) Nature immunology 8, 610-8. PMID: 17486091 3. Drage, MG. et al. (2009) Cellular immunology 258, 29-37. PMID: 19362712 4. Chen, ST. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 668-77. PMID: 22174456 5. Deboosère, N. et al. (2017) Cellular microbiology 19. PMID: 27220037 | ||||
| Примечание | For research use only | ||||
| Isotype Control | Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207) |

SDS-PAGE for Anti-Mouse CD282/TLR2 Antibody (SAA2382)




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