Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013)

Name: Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3)
Brand: abinScience
SKU: MT070013
Price: 126 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD): --

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MT070013

Descripción

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013) is a mouse monoclonal antibody detecting Neuropilin-1/NRP1 in ELISA, FCM. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, FCM

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

YW64.3

Objetivo

Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304, NRP1, NRP, VEGF165R

Nivel de endotoxinas

< 10 EU/mg as determined by LAL method.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O14786, P97333

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis.

1. Gagnon, ML. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 2573-8. PMID: 10688880

2. He, Z. et al. (1997) Cell 90, 739-51. PMID: 9288753

3. Soker, S. et al. (1998) Cell 92, 735-45. PMID: 9529250

4. Teesalu, T. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16157-62. PMID: 19805273

5. Issitt, T. et al. (2019) iScience 11, 205-223. PMID: 30623799

Nota

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3)

Referencias

Datasheet

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013)

Vista general

Imágenes

Referencias

Datasheet

SDS