Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013)

Name: Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3)
Brand: abinScience
SKU: MT070013
Price: 126 USD
Availability: InStock

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1mg

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SDS

Aperçu

Numéro de catalogue

MT070013

Description

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013) is a mouse monoclonal antibody detecting Neuropilin-1/NRP1 in ELISA, FCM. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human, Mouse

Applications

ELISA, FCM

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

YW64.3

Cible

Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD304, NRP1, NRP, VEGF165R

Niveau d'endotoxines

< 10 EU/mg as determined by LAL method.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O14786, P97333

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Cell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis.

1. Gagnon, ML. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 2573-8. PMID: 10688880

2. He, Z. et al. (1997) Cell 90, 739-51. PMID: 9288753

3. Soker, S. et al. (1998) Cell 92, 735-45. PMID: 9529250

4. Teesalu, T. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16157-62. PMID: 19805273

5. Issitt, T. et al. (2019) iScience 11, 205-223. PMID: 30623799

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Mouse CD304/NRP1 Recombinant Antibody (YW64.3)

Reférences

Fiche technique

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070013)

Aperçu

Images

Reférences

Fiche technique

SDS