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Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3) (MT070207)

Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3)
Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3)
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Aperçu
Numéro de catalogueMT070207
Reactivité des espècesHuman, Mouse
ApplicationsELISA, FCM
Espèce hôteRat
ClonalitéMonoclonal
IsotypeIgG1, kappa
ID de cloneYW64.3
Cible NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P97333
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis.

1. He, W. et al. (2015) Nature 526, 710-4. PMID: 26503042
Note For research use only.
Images
  • Anti-Mouse Neuropilin-1/NRP1 Recombinant Antibody (YW64.3)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD304/NRP1 Antibody (YW64.3)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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