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Anti-Mouse Neuropilin-1/NRP1/Neuropilin-2/NRP2 Recombinant Antibody (YW68.11.26), PerCP (MT070147)

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Vista general
Número de catálogoMT070147
Reactividad de especiesHuman, Mouse
AplicacionesELISA, FCM
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonYW68.11.26
ConjugaciónPerCP
Objetivo NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor, Vascular endothelial cell growth factor 165 receptor 2, Neuropilin-2, VEGF165R2, NRP2
Nivel de endotoxinas Please contact with the lab for this information.
Productos asociados Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), PerCP
Número de acceso P97333, O35375
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo

Neuropilin-1 (NRP1/NRP2) is a ~103 kDa protein. Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis.

1. He, W. et al. (2015) Nature 526, 710-4. PMID: 26503042
Nota For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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C₁ (Stock Conc.)
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C₂ (Working Conc.)
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