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Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101) (MW338107)

Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101)
Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Vista general

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  • Datasheet

  • SDS

Vista general
Número de catálogoMW338107
Reactividad de especiesMouse
AplicacionesFCM, Neutralization, WB
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonDC101
Objetivo CD309, EC:2.7.10.1, FLK-1, FLK1, Fetal liver kinase 1, KDR, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1, VEGFR-2, VEGFR2, Vascular endothelial growth factor receptor 2
Nivel de endotoxinas < 10 EU/mg
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P35918
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~150 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza).

Nota For research use only.
Imágenes
  • Anti-Mouse VEGFR2/KDR/Flk-1 Recombinant Antibody (DC101)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD309/KDR/VEGFR-2 Antibody (DC101)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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