

| Каталожный номер | MV592014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Mouse CD321/F11R Polyclonal Antibody (MV592014) is a rabbit polyclonal antibody detecting CD321/F11R in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| Реактивность видов | Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Mouse CD321/F11R (Gly53-Glu233). | ||||||||
| Цель | Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD antigen CD321) | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Чистота | >95% as determined by SDS-PAGE. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O88792 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Junctional adhesion molecule A (CD321/F11R) is a ~32 kDa protein. Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. 1. Ebnet, K. et al. (2001) The EMBO journal 20, 3738-48. PMID: 11447115 2. Martìn-Padura, I. et al. (1998) The Journal of cell biology 142, 117-27. PMID: 9660867 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-F11R polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse lung lysate
Lane 2: Rat lung lysate
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