Anti-Mouse FGFR4 Recombinant Antibody (U3-1784), FITC (MB856117)

Name: Anti-Mouse FGFR4 Recombinant Antibody (U3-1784), FITC
Brand: abinScience
SKU: MB856117
Price: 223 USD
Availability: InStock

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Número de catálogo	MB856117
Reactividad de especies	Human, Mouse, Rat
Aplicaciones	ELISA, FCM
Especie huésped	Rat
Clonalidad	Monoclonal
Isotipo	IgG1, kappa
ID de clon	U3-1784
Conjugación	FITC
Objetivo	FGFR4, Fibroblast growth factor receptor 4, TKF, FGFR-4, JTK2, CD334
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), FITC
Número de acceso	Q03142
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Fibroblast growth factor receptor 4 (CD334/FGFR4) is a ~88 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Mouse FGFR4 Recombinant Antibody (U3-1784), FITC.pdf

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