Anti-Mouse FGFR4 Recombinant Antibody (U3-1784), PerCP (MB856147)

Name: Anti-Mouse FGFR4 Recombinant Antibody (U3-1784), PerCP
Brand: abinScience
SKU: MB856147
Price: 268 USD
Availability: InStock

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Каталожный номер	MB856147
Реактивность видов	Human, Mouse, Rat
Применения	ELISA, FCM
Хозяинский вид	Rat
Клоональность	Monoclonal
Изотип	IgG1, kappa
ID клона	U3-1784
Конъюгация	PerCP
Цель	FGFR4, Fibroblast growth factor receptor 4, TKF, FGFR-4, JTK2, CD334
Уровень эндотоксинов	Please contact with the lab for this information.
Связанные продукты	Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), PerCP
Номер доступа	Q03142
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Store at 4°C for 12 months. Protect from light. Do not freeze.
Фон	Fibroblast growth factor receptor 4 (CD334/FGFR4) is a ~88 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. Phosphorylates PLCG1 and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate.
Примечание	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse FGFR4 Recombinant Antibody (U3-1784), PerCP.pdf

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