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Anti-Mouse CD35 Recombinant Antibody (7G6) (MB625107)

Anti-Mouse CD35 Recombinant Antibody (7G6)
Anti-Mouse CD35 Recombinant Antibody (7G6)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

  • SDS

Vista general
Número de catálogoMB625107
Reactividad de especiesMouse
AplicacionesELISA, FCM
Especie huéspedRat
ClonalidadMonoclonal
IsotipoIgG2b, kappa
ID de clon7G6
Objetivo Complement receptor type 1, C3b/C4b receptor, CD35, CR1, C3BR
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P19070
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Complement receptor type 2 (CD35/CR1) is a ~112 kDa protein. Serves as a receptor for various ligands including complement component CD3d, HNRNPU OR IFNA1. When C3d is bound to antigens, attaches to C3d on B-cell surface and thereby facilitates the recognition and uptake of antigens by B-cells. This interaction enhances B-cell activation and subsequent immune responses. Forms a complex with several partners on the surface of B-cells including CD19, FCRL5 and CD81, to form the B-cell coreceptor complex that plays a crucial role in B-cell activation and signaling. Also induces specific intracellular signaling separately from the BCR and CD19 by activating the tyrosine kinase SRC, which then phosphorylates nucleolin/NCL and triggers AKT and GSK3 kinase activities in a SYK/CD19-independent manner.

Nota For research use only.
Imágenes
  • Anti-Mouse CD35 Recombinant Antibody (7G6)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD35/CR1/CD21b Antibody (7G6)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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