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Anti-Mouse CD36 Polyclonal Antibody
Anti-Mouse CD36 Polyclonal Antibody
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Обзор
Каталожный номерMB030014
Реактивность видовMouse, Rat
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant Mouse CD36 (Lys56-Gly423).
Цель Cd36
Очистка Purified by antigen affinity column.
Номер доступа Q08857
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Platelet glycoprotein 4 (CD36) is a ~52 kDa protein. Multifunctional glycoprotein that acts as a receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor-ligand complexes. The dependency on coreceptor signaling is strongly ligand specific. Cellular responses to these ligands are involved in angiogenesis, inflammatory response, fatty acid metabolism, taste and dietary fat processing in the intestine (Probable).

1. Endemann, G. et al. (1993) The Journal of biological chemistry 268, 11811-6. PMID: 7685021
2. Jimenez-Dalmaroni, MJ. et al. (2009) PloS one 4, e7411. PMID: 19847289
3. Stewart, CR. et al. (2010) Nature immunology 11, 155-61. PMID: 20037584
4. Heit, B. et al. (2013) Developmental cell 24, 372-83. PMID: 23395392
5. Wang, J. et al. (2019) Cell reports 26, 209-221.e5. PMID: 30605677
6. Hao, JW. et al. (2020) Nature communications 11, 4765. PMID: 32958780
7. Nassir, F. et al. (2007) The Journal of biological chemistry 282, 19493-501. PMID: 17507371
8. Masuda, D. et al. (2009) Journal of lipid research 50, 999-1011. PMID: 18753675
9. Tran, TT. et al. (2011) The Journal of biological chemistry 286, 25201-10. PMID: 21610069
10. Laugerette, F. et al. (2005) The Journal of clinical investigation 115, 3177-84. PMID: 16276419
Примечание For research use only.
Изображения
  • Anti-Mouse CD36 Polyclonal Antibody

    Western blot

    Western blot analysis was performed using anti-CD36 polyclonal antibody at 1µg/ml on various samples.
    Lane 1: Mouse lung lysate
    Lane 2: Mouse heart lysate

Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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