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| カタログ番号 | MY570014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse CD79α/CD79A Polyclonal Antibody (MY570014) is a rabbit polyclonal antibody detecting CD79a in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD79α/CD79A (Ser37-Asn121). | ||||||||
| ターゲット | Surface IgM-associated protein, CD79a, Membrane-bound immunoglobulin-associated protein, MB1, MB-1 membrane glycoprotein, IGA, CD79A, Ig-alpha, B-cell antigen receptor complex-associated protein alpha chain | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11911 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | B-cell antigen receptor complex-associated protein alpha chain (CD79α/CD79A) is a ~24 kDa protein. Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. | ||||||||
| 注意事項 | For research use only. |
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