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Anti-Mouse CD79B Recombinant Antibody (HM79-16), PE (MW431127)

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Aperçu
Numéro de catalogueMW431127
Reactivité des espècesMouse
ApplicationsFCM
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, lambda
ID de cloneHM79-16
ConjugaisonPE
Cible B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, Igb
Niveau d'endotoxines Please contact with the lab for this information.
Produits associés Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), PE
Numéro d'accès P15530
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~25 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy).

Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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