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| カタログ番号 | MW431014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Mouse CD79β/CD79B Polyclonal Antibody (MW431014) is a rabbit polyclonal antibody detecting CD79b in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 種反応性 | Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Mouse CD79β/CD79B (Val26-Ser145). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, Cd79b, Igb | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P15530 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~25 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy). | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-CD79B polyclonal antibody at CD79B on various samples.
Lane 1: Daudi cell lysate
Lane 2: HL-60 cell lysate
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