Anti-Mouse B7-1/CD80 Recombinant Antibody (16-10A1) (MW630107)

Name: Anti-Mouse B7-1/CD80 Recombinant Antibody (16-10A1)
Brand: abinScience
SKU: MW630107
Price: 163 USD
Availability: InStock

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Vista general

Número de catálogo	MW630107
Marca	abinScience
Reactividad de especies	Mouse, Canine
Aplicaciones	FCM
Especie huésped	Armenian Hamster
Clonalidad	Monoclonal
Isotipo	IgG
ID de clon	16-10A1
Objetivo	CD80, BB1, T-lymphocyte activation antigen CD80, CD28LG, B7, CD28LG1, LAB7, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	Q00609
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	T-lymphocyte activation antigen CD80 (B7-1) is a ~34 kDa protein. Costimulatory molecule that belongs to the immunoglobulin superfamily that plays an important role in T-lymphocyte activation. Acts as the primary auxiliary signal augmenting the MHC/TCR signal in naive T-cells by acting as a ligand for the CD28 receptor which is constitutively expressed on the cell surface of T-cells. In turn, activates different signaling pathways such as NF-kappa-B or MAPK leading to the production of different cytokines. Also acts as an inhibitor of T-cell activation by acting as a ligand for CTLA4, a decoy receptor, thereby blocking CD28-mediated T-cell priming. In addition, CD28/CD80 costimulatory signal stimulates glucose metabolism and ATP synthesis of T-cells by activating the PI3K/Akt signaling pathway. 1. Tseng, SY. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7829-36. PMID: 16339518 2. Freeman, GJ. et al. (1991) The Journal of experimental medicine 174, 625-31. PMID: 1714935 3. Good-Jacobson, KL. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 4217-25. PMID: 22450810
Nota	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Mouse CD80/B7-1 Antibody (16-10A1)

Referencias

Datasheet

Anti-Mouse B7-1/CD80 Recombinant Antibody (16-10A1).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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