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Anti-Mouse CD83 Recombinant Antibody (SAA2066) (MX237107)

Anti-Mouse CD83 Recombinant Antibody (SAA2066)
Anti-Mouse CD83 Recombinant Antibody (SAA2066)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
Número:
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  • SDS

Vista general
Número de catálogoMX237107
Reactividad de especiesHuman, Mouse
AplicacionesFCM
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG1, kappa
ID de clonSAA2066
Objetivo CD83, hCD83, CD83 antigen, B-cell activation protein, Cell surface protein HB15
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso O88324
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

CD83 antigen is a ~21 kDa protein. Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8. Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII. In addition, acts as an important modulator of protective responses against acute infections.

1. von Rohrscheidt, J. et al. (2016) The Journal of experimental medicine 213, 1685-94. PMID: 27503071
2. Liu, H. et al. (2016) The Journal of experimental medicine 213, 1695-703. PMID: 27503069
3. Wild, AB. et al. (2019) JCI insight 4. PMID: 31527313
Nota For research use only.
Imágenes
  • Anti-Mouse CD83 Recombinant Antibody (SAA2066)

    SDS-PAGE

    SDS-PAGE for Anti-Mouse CD83 Antibody (SAA2066)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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