

| Каталожный номер | MX237107 |
|---|---|
| Реактивность видов | Human, Mouse |
| Применения | FCM |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| ID клона | SAA2066 |
| Цель | CD83, hCD83, CD83 antigen, B-cell activation protein, Cell surface protein HB15 |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | O88324 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Фон | CD83 antigen is a ~21 kDa protein. Transmembrane glycoprotein predominantly found on the surface of many immune cells including dendritic cells or lymphocytes that plays various roles in immune response regulation. Plays an essential role in CD4(+) T-selection, differentiation and stability by regulating the activity of the major E3 ubiquitin ligase responsible for controlling MHC II trafficking MARCHF8. Also inhibits MARCHF1 association with MHC II and ubiquitination of MHCII. In addition, acts as an important modulator of protective responses against acute infections. 1. von Rohrscheidt, J. et al. (2016) The Journal of experimental medicine 213, 1685-94. PMID: 27503071 2. Liu, H. et al. (2016) The Journal of experimental medicine 213, 1695-703. PMID: 27503069 3. Wild, AB. et al. (2019) JCI insight 4. PMID: 31527313 |
| Примечание | For research use only. |

SDS-PAGE for Anti-Mouse CD83 Antibody (SAA2066)




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